genetic manipulation...we need to come to an agreement here!

jverne

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read (it's quite long, but very interesting)

?The advance of genetic engineering makes it quite conceivable that we will begin to design our own evolutionary progress.?

~Isaac Asimov, famous thinker and sci-fi writer

Cornell University researchers in New York revealed that they had produced what is believed to be the world?s first genetically altered human embryo?an ironic twist considering all the criticism the US has heaped on South Korea over the past several years for going ?too far? with its genetic research programs. The Cornell team, led by Nikica Zaninovic, used a virus to add a green fluorescent protein gene, to a human embryo left over from an in vitro fertilization procedure. The research was presented at a meeting of the American Society of Reproductive Medicine last year, but details have emerged only after new controversy has emerged over the ethics and science of genetically modifying humans.

Zaninovic has pointed out that in order to be sure that the new gene had been inserted and the embryo had been genetically modified, scientists would ideally want to keep growing the embryo and carry out further tests. However, the Cornell team did not get permission to keep the embryo alive. The GM embryos created could theoretically have become the world?s first genetically altered man or woman, but it was destroyed after five days.

British regulators form the Human Fertilization and Embryology Authority (HFEA), have warned that such controversial experiments cause ?large ethical and public interest issues?.

Much of the debate stems from the fact that the effects of genetically altering an embryo would be generational and permanent. In other words, if we create a mutant baby and it grows up to have children of it?s own?they?ll all be mutant gene carriers too. Genes injected into embryos and reproductive cells, such as sperm, affect every cells in the body and would be passed on to future generations. Critics say current humans don?t have the right to tamper with the gene pool of future generations.

On the other hand, proponents of such technology say that this science could potentially erase diseases such as cystic fibrosis, hemophilia and even cancer. In theory, any ?good? gene could be added to embryos to offset any ?bad? genes they are currently carrying. That could potentially mean the difference between life and death for many children.

John Harris, the Sir David Alliance Professor of Bioethics at Manchester University, takes it a step further. He believes that as parents, citizens, and scientists, we are morally obliged to do whatever we can genetically to make life better and longer for our children and ourselves. Society currently devotes so much energy and resources towards saving lives, which, in reality, is simply postponing death, he notes. If it is right to save life, Harris reasons, then it should also be right to postpone death by stemming the flow of diseases that carry us to the grave.

For Harris, having the ability to improve our species lot in life but refusing to do so, makes little sense. He has a difficult time understanding why some people are so insistent that we shouldn?t try to improve upon human evolution.

?Can you imagine our ape ancestors getting together and saying, ?this is pretty good, guys. Let?s stop it right here!?. That?s the equivalent of what people say today.?

Ethicists, however, warn that genetically modifying embryos will lead to designer babies preloaded with socially desirable traits involving height, intelligence and coloring.

Dr David King, director of Human Genetics Alert, warns, ?This is the first step on the road that will lead to the nightmare of designer babies and a new eugenics.?

Harris, however, doesn?t support that argument. He says it?s not about ?beauty? it?s about health, and what parent wouldn?t want a healthy child, he asks.

?Certainly, sometimes we want competitive advantage [for our children], but for the enhancements I talk about, the competitive advantage is not the prime motive. I didn?t give my son a good diet in the hope that others eat a bad diet and die prematurely. I?m happy if everyone has a good diet. The moral imperative should be that enhancements are generally available because they are good for everyone.?

The only other route to equality, he says, is to level down so that everyone is as uneducated, unhealthy and unenhanced as the lowest in society ? which would be much more unethical in his opinion. Even though we can?t offer a liver transplant to all who need them, he says, we still carry them out for the lucky few. ?Much better to try to raise the baseline, even if some are left behind.?

The Human Fertilization and Embryology Bill in currently under consideration in Britain will likely make it legal to create GM embryos in that country, but only for research?implantation in the womb will still be banned?at least for now. However, ethicists believe that the legislation could easily be relaxed even further in the future.

People who believe that genetically modified humans is something way into the future might want to consider that many experts are worried that some forms of it are already happening in the sports world.

Faster, bigger, better, stronger?in theory, the single most effective way to radically alter your physical capacities is to manipulate your genes. Athletes are beginning to take notice. Now that we?ve mapped out the human genome and identified exactly which genes make you buff, tough and rough?experts are concerned about the future of genetic doping.

Gene doping could spawn athletes capable of out-running, out-jumping and out-cycling even the world?s greatest champions. However, researchers at the University of Florida are attempting to prevent that from happening by detecting the first cases of gene doping in professional athletes before the practice becomes mainstream.

Montreal-based World Anti-Doping Agency (WADA), responsible for monitoring the conduct of athletes, is working with investigators around the globe to develop testing to identify competitors who have injected themselves with genetic material that is capable of enhancing muscle mass or heightening endurance.

?If an athlete injects himself in the muscle with DNA, would we be able to detect that?? asked one of France?s leading gene therapy researchers, Philippe Moullier, M.D., Ph.D., director of the Gene Therapy Laboratory at the Universite de Nantes in France.

Right now, he says the answer is clearly ?no?. But that may soon change. The UF scientists are among several groups collaborating with national and global anti-doping organizations to develop a test that can detect evidence of ?doped? DNA.

?WADA has had a research program in place for some years now, to try to develop tests for gene-based doping,? said Theodore Friedmann, M.D., head of the agency?s panel on genetic doping and director of the gene therapy program at the University of California, San Diego.

Nearly every day now we are inundated with new genetic discoveries. Scientists can now pinpoint many specific genes including being lean, living a long life, improved self-healing, thrill seeking behavior, and having an improved memory among many other incredible traits. Many believe that these genes can be manipulated in ordinary humans, in effect creating Super-Mutants.

Theoretically, options are nearly limitless. Even a gene that exists in another species could be brought over to a human cell. Imagine some of the incredible traits of the animal kingdom that some humans don?t possess such as night vision, amazing agility, or the ability to breath underwater. The precedence for these types of radical changes is already in place. Experimental mice, for example, were successfully given the human ability to see in color. If animals can be engineered to have human traits, then humans can certainly be mutated to have desirable animal traits.

It is even thought possible to so drastically alter human genomes that a type of superhuman species could emerge. The fear with germline engineering is that since it is inheritable, offspring and all succeeding generations would carry the modified traits. This is one reason why this type of engineering is currently banned- it could lead to irreversible alteration of the entire human species.

Ethics, not scientific limitations, is the real brick wall. Most scientists believe manipulating genes in order to make an individual healthy is a noble and worthwhile pursuit. Some are against even that notion, arguing that historically amazing individuals have sometimes been plagued by genetic mental and physical disorders, which inadvertently shaped the greatness of their lives. Should we rob the human race of character shaping frailty? Very few scientists would dare to publicly endorse the idea of using genetic engineering to make a normal, healthy individuals somehow superior to the rest of the human race.

?The push to redesign human beings, animals and plants to meet the commercial goals of a limited number of individuals is fundamentally at odds with the principle of respect for nature,?
said Brent Blackwelder, President of Friends of the Earth in his testimony before the Senate Appropriations Committee.

However, would it be so bad if the human race were slightly improved? What if a relatively simple procedure could make an individual and his or her offspring resistant to cancer? After all, Nature isn?t always right. Nature has naturally selected many people to carry the burden of uncomfortable and often lethal genetic disorders. If nature knows best, then shouldn?t we quit trying to ?improve? upon nature by ?curing? people of genetic conditions we consider inferior? Many say we shouldn?t change human genetics, UNLESS it?s the RIGHT thing to do. Who gets to decide where the line is between righteous endeavor and the corruption of nature? These are the questions facing our generation.


http://www.dailygalaxy.com/my_weblog/2009/03/the-worlds-fi-1.html

also check out the links at the bottom of the page (giving mice color sight and stuff)


how do we manage this?

personally i see this as a huge problem.
with such a social and economic system we have i see a lot of potential for exploitation. we might try to regulate this but eventually the rules will loosen up under the power of corporate influence.

as for the neo eugenics issue...if it will be controlled and available to all then we might give it a go. most of the shit will fall on the transitional generations...which are generations from the 20', 30' and 40' of this century...basically our grandsons. once everybody has been altered a new standard will arise.

thing is that it won't affect us, well be dead or dying before the first usable genetically manipulated child will come of age. so there's a big chance i'm acting out of fear here...

i'd conclude that we shouldn't go forward with it until humanity as a whole will drastically change its current views. (which will probably happen far too late)

oh and did i mention that the first country('s) to have a substantial population of "superhumans" will probably look down on poorer ones. (even more than today)
 
pretty sweet huh? even though it's a movie, I can really see that happening in the future. Life would be awful for the non-altered.
 
Yes, humanity is not ready to survive this. Neither were we ready to survive the invention of firearms, nuclear power, and computer driven robots.

This is the same kind of fear that drives the "books/music/tv/video games are destroying our kids!!" panic fest.

Humans destroying humanity is everyone's favorite fantasy of all time, but every time people freak out about it, it never comes to fruition. This will be no different. As with everything we do, we will better ourselves with this power just as much as we harm ourselves with it. In the end, we will be no better off than we were before, and no worse off. It will just be different.
 
I agree we won't destroy ourselves. But like Jverne said, most of the shit will fall on the transitional generations. At first, altered people will be seen as freaks. Then when it is about 50/50, tensions between the two groups will be very high. Finally, when almost everybody is altered, the non-altered will be seen as sub-humans.

This doesn't mean I'm against it though. even with all of that, it would be stupid not to improve ourselves if possible.

I change my mind about destroying ourselves. It wont be problem unless someone tries to bring dinosaurs back to life. I MEAN, DID YOU SEE THOSE RAPTORS IN JURASSIC PARK? THEY F***ED THAT GUY UP!
 
But like Jverne said, most of the shit will fall on the transitional generations. At first, altered people will be seen as freaks. Then when it is about 50/50, tensions between the two groups will be very high. Finally, when almost everybody is altered, the non-altered will be seen as sub-humans.

Well yeah, but thats unavoidable. If we wait for humans to become accepting of others, then we might as well forget about it, because that will never happen.
 
Healing sickness is always something I'm for. AIDS resistance would be excellent for third-world countries, because with more resistance to diseases and some outside help, they might finally be able to start developing.
As for non-essential betterment, I think it starts a slippery slope. Sure, I'd be interested to see what kinda things people could come up with (Night vision, **** yes! Gills? also **** yes!), but in the end it will always get out of hand. In fact, I'd be all for innovation like that, if it were the parent's wishes, and they could live with their child potentially smelling like fish for the rest of their life. But just improving on what we already have, that should probably not be allowed for anyone.
 
i heard you can buy kits of material and just like Crystal Meth labs are so easy to make, so are altering ones genes. Also read the book NEXT by Michael Crichton. very good book on Genetic Manipulation. also gotta love the show Fringe (kinda lost track of it, but good show)
 
What? You'd need to change every specific cell to show the effect the specific trait. Otherwise do it at the embryonic stage. How do you propose getting the egg out of the woman with household crap?
 
what happens when everyone lives to be 1,000 years old and not one person has a disease

will we go to war with each other because we are bored?? or will we try to live even longer?? immortality is never going to happen and extinction is always around the corner
 
I think that we should certainly rid ourselves of diseases and such. Though we're already ****ed by over population as it is. And Lets say we populate Mars, I doubt it would take that long to populate the hell out of it as well since we've already go so many people.
 
Populating Mars would be harder than populating earth. its also smaller than Earth and realistically there are more moons around Saturn and Jupiter that are more our size and some that might even hold a closer composition. But i do say we should populate the moon first, then mars, and head that way. Venus may be a waste of time because of the heat and pressure. also we should try to own the solar system before we even dream of getting to the next star.
 
Yeah, it'd be nice to get the technology to gtfo out of here faster than light though. Maybe the LHC will make wormholes for us!
 
Yeah, it'd be nice to get the technology to gtfo out of here faster than light though. Maybe the LHC will make wormholes for us!

what better technology than the one that unites humanity in EPIC FAILURE?? Amirite??
 
if the majority of people are evil, and hes helping us, then we're SAVED!!!! WAHOO!!!
 
I agree we won't destroy ourselves. But like Jverne said, most of the shit will fall on the transitional generations. At first, altered people will be seen as freaks. Then when it is about 50/50, tensions between the two groups will be very high. Finally, when almost everybody is altered, the non-altered will be seen as sub-humans.

This doesn't mean I'm against it though. even with all of that, it would be stupid not to improve ourselves if possible.

This.

At the end of the day though, if humanity can genetically manipulate itself for the better then fine.

Its no different then harnessing technology for our own benefit, nobody complains about increasingly more advanced artificial hearts, limbs and the likes, laser eye surgery, sophisticated surgical techniques in general, so on so on.

It'll create problems for sure, but then something always does, some people will always find some excuse to discriminate (religion, race, sex, what-have-you) but genetic engineering isn't going to create super-mutants, merely improve our health and what-have-you and if modern developed societies can overall be beyond petty racism, then I think society can live with Jim from next door being genetically protected against hereditary cancers.
 
Humans aren't meant to play God. Besides, I thought the manipulation of human embryos was illegal in the first place?
 
So much misinformation in that article it's horrible. Also some of you need to read a bit less X-Men.


Sigh, humans. :dozey:
 
Who says humans aren't meant to play god?

Being God gives absolute power. Absolute power corrupts humans absolutely, I definitely don't want a totally bent nutcase who is capable of ****ing over the natural order of stuff more than we already have.
 
I definitely don't want a totally bent nutcase who is capable of ****ing over the natural order of stuff more than we already have.

So... you're not a huge fan of God then?



Zing.



But the designer genetics thing would be going too far - wouldn’t it lead to generations of people with very similar fashionable traits, eliminating a lot of the diversity and happy accidents that make real evolution happen? Sounds like it’d leave us fairly vulnerable as a species

I dont see how it would make us any more vulnerable. I mean, humans deciding how we evolve is just the next step in natural evolution. And we can identify threats to our species a lot quicker than the trial and error method of nature.

More likely, it’d just be the lucky few who have access to it and we’ll be stuck with a load of genetically superior jerks running things

Again, this is inevitable. But it wont stay that way for very long. People thought cars were going to be rich people only devices too.
 
Being God gives absolute power. Absolute power corrupts humans absolutely, I definitely don't want a totally bent nutcase who is capable of ****ing over the natural order of stuff more than we already have.

Yeah but we're only playing god. We don't actually have absolute power.
 
Noooooooo!!! When we allow genetic manipulation, I'll bet you all my moneybucks that the first thing that will happen is that furries will grow themselves cat tails and ears! We can't let them win!
 
What a shit video. Sensationalist fearmongering with distorted/out of context/completely made up information.
 
Genetic manipulation for improving our health eradicating disease, prolonging our lifespans, I'm all for it. However laws have to be set up to prevent discrimination, otherwise we'll have a Gattaca like scenario unfold, at least until everyone is genetically enhanced...
 
Humans aren't meant to play God. Besides, I thought the manipulation of human embryos was illegal in the first place?


Don't be silly, God doesn't exist, how can you play that which has no existence?.


If humans wanna tamper with our genetics then we can bloody well tamper with our genetics.

I never got the "its toying with the natural order of things" argument, I mean, take a look around, we've been tampering with the "natural order" since we first stuck a sharpened stone to the end of a stick and realized a cliff edge can kill a mammoth easier then jumping on it and screaming like a moron hoping it'll die from shock.
 
What a shit video. Sensationalist fearmongering with distorted/out of context/completely made up information.

sir you're a naive smuck. sure the video get's mystical at times...but when interviewing more credible sources it raises quite some interesting points.

i'll get into more details later (cause i'm going out right now), but from the initial impressions it is just what i'm talking about...corporations and genetic manipulation just don't mix.

to give you a bone to chew in the meantime...how do you argument that companies doing the research are making their own safety tests and are not regulated whatsoever? that goes especially true for the US where government control is not that widespread.
it goes for all of the world but it's just more typical for the US...companies invent something, **** it up and only then regulations are established.

i happen to quite agree with the opinion that biologic pollution does not dilute trough time (like chemical) it just get's worse...because living beings are self replicating.

humans are not capable enough to carry out such fundamental changes in such a short time. nature went trough a painstaking process of weeding out the undesirable traits, we think we can do better in just...what...3 decades???
like i said...the important fact is that biologic pollution is not self diluting, even if the might make self terminating organisms, with our current tech there can be no 100% consistency.

as i said...i'm not against genetic manipulation. it's just that i don't want it happen so fast or lead by profit based companies or poorly/non regulated.
corporations are doing just the opposite...fast introduction, poorly regulated and negligent.
(now you're probably gonna say...but corporations are not evil, and that shit...of course they aren't, it's just that they don't give a **** about you until they can drain you of money)

and besides...self terminating plants are a godsend to them...they have the excuse that they wont spread and at the same time they can be a monopolist.

and besides how can you approve of the patent practices being used nowadays, i've already shown instances where companies tried to gain a patent on someones genes and other stuff.

sir...i'm shocked at your close mindness and naivety. (if of course you happen to believe in what i'm accusing you of, otherwise i suggest you explain yourself better)
 
Jverne, I get the feeling that you're just reacting out of knee-jerk panic. First off, how can anyone regulate something which we hasnt even come close to being a normal practice? A lot of what you're worried about will probably be taken care of by the time genetic manipulation is feasible in any amount beyond tests and experiments. We do still have a long time to go before that happens.

And secondly,

humans are not capable enough to carry out such fundamental changes in such a short time. nature went trough a painstaking process of weeding out the undesirable traits, we think we can do better in just...what...3 decades???

What are you basing this assumption off of? We've never been faced with a situation like this before, so how can you presume on our ability to handle it? Just because nature is slow doesnt mean its better. In fact, its ****ed up countless times, literally.
 
sir you're a naive smuck. sure the video get's mystical at times...but when interviewing more credible sources it raises quite some interesting points.

i'll get into more details later (cause i'm going out right now), but from the initial impressions it is just what i'm talking about...corporations and genetic manipulation just don't mix.

to give you a bone to chew in the meantime...how do you argument that companies doing the research are making their own safety tests and are not regulated whatsoever? that goes especially true for the US where government control is not that widespread.
it goes for all of the world but it's just more typical for the US...companies invent something, **** it up and only then regulations are established.

i happen to quite agree with the opinion that biologic pollution does not dilute trough time (like chemical) it just get's worse...because living beings are self replicating.

humans are not capable enough to carry out such fundamental changes in such a short time. nature went trough a painstaking process of weeding out the undesirable traits, we think we can do better in just...what...3 decades???
like i said...the important fact is that biologic pollution is not self diluting, even if the might make self terminating organisms, with our current tech there can be no 100% consistency.

as i said...i'm not against genetic manipulation. it's just that i don't want it happen so fast or lead by profit based companies or poorly/non regulated.
corporations are doing just the opposite...fast introduction, poorly regulated and negligent.
(now you're probably gonna say...but corporations are not evil, and that shit...of course they aren't, it's just that they don't give a **** about you until they can drain you of money)

and besides...self terminating plants are a godsend to them...they have the excuse that they wont spread and at the same time they can be a monopolist.

and besides how can you approve of the patent practices being used nowadays, i've already shown instances where companies tried to gain a patent on someones genes and other stuff.

sir...i'm shocked at your close mindness and naivety. (if of course you happen to believe in what i'm accusing you of, otherwise i suggest you explain yourself better)

There's a lot more regulation in the release of a GM crop than you might think, at least in the majority of countries. I've been lectured by one of the main men in the Golden Rice project team, did you know it takes about 10 years and millions of dollars before a GM crop will be approved for argictultural use? You have to go through the same process ineach country you want to grow it in too. In fact even non-GM crops go through long certification processes when a new cultivar is developed.

What's this bullshit about 'pollution'? You think GM wheat will somehow cause 'natural' wheat to stop growing in the wild or something? :LOL: :LOL:
The video is laughable, without even the slightest pretense at trying to present a balanced case. Did you see the part where some organic farmer was complaining that the Big Evil Corporation failed to warn his neighbour that if he planted GM crops the seeds could grow in soil elsewhere? As if farmers would be ignorant of that?
Or where the other organic farmer was saying that there's almost no 'pure' canola grown in Canada anymore? Could that be because most farmers prefer better yielding GM varieties? No, obviously the Big Bad Corporations are holding them at gun-point.

Honestly I do have some misgivings about these multinationals having such limited competition in the field of GM development - but that's the fault of Governments, anti-GM NGOs and the public.
If governments didn't make it prohibitavely costly for startup biotech companies to develop GM you would have less of those problems. If NGOs like Friends of the Earth weren't using scare tactics and demonising GM technology, and if the public didn't buy into their bullshit then we could get far more publicly funded R&D into GM to the same level we do in most other branches of science.

That said the supremacy of the multinationals in this field will be coming to its end. Many asian countries, including China and India, are sinking massive amounts of resources into improving crops - and are looking at less dubious targets than things such as Terminator technologies.

I'm shocked at your gullibility and naivety, falling for the tired propaganda of the environmentalist extremeists. :p
 
Sure, but it's still largely irrelevant. Typical fear of science storytelling. Well done, but don't take it too/i] seriously.
 
Also Gattaca is bullshit.

*single tear slides down the side of face*

But really, I do know what you mean. Even though they weren't completely ridiculous with the manipulations (people with wings, super strength, etc.), the discrimination the invalids faced was a little over the top.
 
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