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[br]An update on the Left 4 Dead 2 blog explains in a little more detail how the concept of Mutations is going to pan out. In a nutshell they will be week-long runs of new gameplay modes where each week one new Mutation is featured and the previous Mutation retired.
Keep an eye on the blog each week for the new mutations, the first of which will be Realism Versus, with 'Chainsaw Massacre' planned later on.Every Thursday the new in-game blog will let you know of the upcoming Mutation. Once a month we will have a poll to vote on your favorite Mutation. The winning Mutation will return the following week.