medicinal mushrooms

thefiznut

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anyone ever taken any? or heard of them?
if you've seen the Paul Stamets video called "6 Ways Mushrooms Can Save The World" you might have heard him mention novel anti-virals produced by medicinally active mushrooms, but apparently it doesn't end there.

I started eating a blend of 17 species and various other mushroom supplements (cordyceps/reishi, and lion's mane) a little over two months ago. I won't go into great detail unless asked but lets just say that my hereditary skin condition previously deemed unresponsive to every drug thrown at it by University of Virginia Medical School's dermatology department, somehow has vanished and i'm not 90%+ clear with no regression. They have also benefited pretty much every other aspect of my life. I experience zero stress, almost no anxiety anymore, and have an enormous abundance of energy with zero fatigue no matter how active I am. I feel emotionally centered or something, every day and my motivational drive is through the roof. Basically they have transformed my immune system into a tank and my entire body and mind is now reaping the rewards slowly (but significantly) over time.
I fully expect to breeze through flu season unscathed, in fact I know so at this point in my research.

Cancer patients benefit GREATLY from the ingestion of quality mushroom mycelia blends made by reputable labs. Many patients have reversed and reduced their cancers, as well as eliminating tumors on top of conjunctive chemo/mushroom treatments, all while breezing through the chemo with insanely high white blood cell counts, and while maintaining a much healthier body while enduring radtiation. Extremely protective, these mushrooms. :)

But hey, read for yourself I suppose:

http://en.wikipedia.org/wiki/Medicinal_mushrooms - good overview
http://www.fungi.com/supplements/info.html - info from stamets site


Sloan Kettering Cancer Center - Reishi Mushroom
Sloan Kettering Cancer Center - Shiitake Mushroom
Sloan Kettering Cancer Center - Maitake Mushroom
Sloan Kettering Cancer Center - Cordyceps Mushroom
Sloan Kettering Cancer Center - Chaga Mushroom
Sloan Kettering Cancer Center - Agaricus Blazei Mushroom
and probably the most important anti-cancer mushroom:
Sloan Kettering Cancer Center - Turkey Tail (Trametes Versicolor)

Cancer.org - Maitake Mushroom
Cancer.org - Shiitake Mushroom

and Cancer Research UK's website has a wonderful PDF overview of the medicinal properties of mushrooms and their role in regulating, stimulating, and awakening the immune system. Quite a mouthful but if you're a stickler for science its a great read..
http://sci.cancerresearchuk.org/labs/med_mush/med_mush.html


Mushroom teas and extracts have been used traditionally by the Chinese and Japanese for several thousands of years, and were highly regarded as one of their best tonics and treatments, especially by royalty and warriors who had exclusive access to them. They purported that the mushrooms strengthened the body and mind, and prevented disease..
After taking them for two months I now have no doubt about their efficacy, and I have always been a skeptical hard-ass when it comes to bullshit homeopathic and natural medicines. I more often than not sit on James Randi's side of the fence. The claims are absolutely correct, just watch out for the quacks all over the internet. Tons of sites just copy/pasting what the biologists and mycologists are writing and hacking it all up.
 
Oh and one last thing: be weary of the FDA when it comes to these things..
In researching the medicinal compounds in mushrooms i've discovered that the FDA is actively ignoring the tips from biologists in the US. It's obvious that these mushrooms pose great thread to the pharmaceutical industry in doing adaptively what their targeted antibiotics, anti-bacterials, and anti-virals do, but doing it better. There's a study done with the Department of Defense testing the Agarikon mushroom against smallpox and other viruses which revealed tremendously high anti-viral activity. Mind-blowing kind of anti-viral activity, actually.
 
There's a mushroom outback growing on a tree. Should I eat it? It's albino white and looks like a pecker.
 
absolutely not. :)

unless you've identified the species and know its edible.

eat a death cap or destroying angel and you'll probably die in 2 weeks and noone will know why your liver failed.
 
Do you know any place to identify them, perhaps narrow the various species down by location? I live near you. Also, do you grow or harvest any of your own mushrooms?
 
Yes, get the National Audubon Society's Field Guide to Mushrooms and a couple books from your local library on mushroom identification. Study up and be thorough, you do NOT want to eat a poisonous mushroom. Your chance of survival would be slim because doctors wouldn't know what you ate and poisonous shrooms unload toxins on your liver weeks after being dormant in your body, out of nowhere.

I'm ordering spores and have plans to cultivate medicinal mushrooms in laboratory conditions following the path being laid by mycologists currently doing the same. I'm reading through Stamets own book on mushroom cultivation, and following his guidelines. He's the words leading expert on mushroom cultivation and has 35 years studying fungi under his belt, so its a safe bet in my eyes. Coincidentally this is not the first time I have grown mushrooms, though that is better discussed elsewhere. :)

I will tell you that just any old mushroom is NOT going to provide you with the medicinal qualities you need to fight disease. You need the correct species, and that means reishi, cordyceps (planet earth insect fungus anyone?), maitake, enokitake, lions' mane, shiitake, turkey tails, birch polypores, oyster, ice man, and others. Also note that eating mushrooms currently circulating in our food supply as edibles (button, portabella, etc) is doing more harm than good. They provide excellent nutrition, but unfortunately are widely known to harbor contaminants that are detrimental to human health.


For those who are curious, here's my daily regimin:

4 per day = http://www.iherb.com/Fungi-Perfecti-Host-Defense-MyCommunity-120-Veggie-Caps/21448?at=0 -

2 per day = http://www.iherb.com/Host-Defense-Cordychi-60-Veggie-Caps/21450?at=0

2 per day = http://www.iherb.com/Host-Defense-Lion-s-Mane-60-Veggie-Caps/21455?at=0

And then I eat:
4000 mg of New Chapter Fish Oil (Omega 3-9) per day
3 Astragalus Root Extract capsules per day (another immunomodulator)
Dr. Ohhira's Professional Formula Probiotic

The last three is something I added as support on top of my mushroom regimin. I noticed significant changes in my physiological responses to stress, pain, healing rates, inflammation, internal body temprature, and more early on even in the first month of eating mushroom supplements. I think the fish oil, astragalus, and probiotic cultures have strengthened my body even more.

There is a lot of evidence suggesting that mushrooms work best in conjunctive therapies, meaning they have a tendency to syngergize with other treatments accelerating and making them more effective. They also synergize with eachother (as well as green tea and vitamin C, suggested by studies) hence why its better to eat all 17 species daily rather than just getting a reishi supplement and pounding it down every day.
 
Oh and before anyone starts.. I am not a quack, I have been a HL2.net member for many years now popping and out over the years.
I don't wish to give blind medical advice or promise any one of you that these mushrooms can help your disease/disorder, but having experienced a powerful change in how I live my life after 2 months of ingestion of these mushrooms, I can absolutely promise you that they were not eaten for thousands of years by asians for nothing..

If you have a disease or disorder, or if you struggle with fatigue, tiredness, lack of mental clarity, stress, anxiety, blood sugar, inflammation, cholesterol, weight gain, etc.. you should SERIOUSLY consider adding medicinal mushrooms into your diet. My roomate noticed my health turning 180 degrees and asked me to provide him with the same dosages I eat daily.. our dog now eats a mushroom supplement powder in her food daily to combat histamine release of bug bites and allergic reactions, as well as weakened cardiovascular health due to heartwork treatments over 3 months.

At this point i'm wondering if they haven't been a factor in the productivity of asian societies.. My bosses have noticed my work performance absolutely blow through the roof.
 
It's great when you see those mushrooms that are labeled "Edible, but eat at your own risk."
 
Yeah, makes you wonder. ;)
More often than not they would be perfectly fine to eat.. but its just not worth the risk when poisonous mushrooms produce such medically evasive and deadly compounds..

In other news, psilocybe mushrooms have been almost 100% effective in curing people with cluster headaches.. a drug is in the works that is essentially psilocybin mushrooms that have been rendered non-psychoactive. This is wonderful news for sufferers of cluster headaches as until now there's been zero cures or treatments found.
 
One last thing before I go for a swim.. And I will emphasize this out of my compassion for all living beings who suffer, and my concern for the Earth that we all share:

If any of you on HL2.net has a relative for friend who has cancer, no matter the severity or treatment they are currently experiencing, please if only for me, Zachary from Southwest Virginia USA, (and god damnit you can freely call me about this) spend the money to get mushroom supplements containing 14 species or more in their daily diet as well as Active Hexose Correlated Compound (AHCC), the Shiitake-derived beta-glucan blend currently used in national conjunctive cancer therapies used in Japan. And get them as much as you can reasonably afford, the more the better their chances. And do this before, during, and after chemo therapy. Due to corporate ignorance of the common good, you will probably not be recommended this treatment. Your doctor may even act like you are crazy. But there is a LOT (some of which I posted above, but feel free to explore PubMed, query any of the species names and read) of global research verifying anti-cancer, anti-tumor, and immunoprotective compounds within mushrooms. I can not guarantee you that it will save them, but I can guarantee you that their chance of survival will be far superior than without. I just happen to feel very, very strongly that they will survive their cancer.

And this guy feels pretty much the same way:
http://www.youtube.com/watch?v=hoJ2TgNdFh8


Also, read the summaries of published AHCC research found on this page:
http://ahccresearch.com/published-studies.php

In a study conducted by the Kansai Medical University in Japan, AHCC was administered to 127 patients with gastric and breast cancers over a period of 3 years. At the end of the period, the Mean Survival Rates (MSRs) of the patients taking AHCC were compared with the average survival times found among patients with the same profile. The study found that the Stage III and IV patients in the AHCC group had more than 40% higher mean survival rates than the average patient without the benefit of supplementation.

The animal studies on AHCC have shown similar clinical outcomes and similar effects on the immune system as in the available human studies. Research on the synergistic effect of using AHCC with conventional chemotherapy in a breast cancer model using rats showed that AHCC can increase the effectiveness of this type of conventional therapy. The most important finding in this study was that the combination of AHCC plus the drug inhibited metastasis of the cancer to distant organs and the lymph nodes. One of the problems of many types of chemotherapy is that it suppresses immune system activity. They found that the cancer drug, UFT (tegafur and uracil), slows down NK cell activity. NK cells are white blood cells that destroy cancer cells. AHCC combined with UFT restored NK cell activity and other immune factors to normal levels. Tumor size was significantly decreased in the AHCC plus UFT group but not in the UFT alone or control groups. Survival rates were significantly increased in the AHCC plus UFT group compared to UFT alone. AHCC was also found to induce white blood cells to increase nitric oxide production. Nitric oxide is an important messenger molecule involved in many physiological and pathological processes, and is beneficial in some types of cancer.

Medical researchers at Yale University together with researchers in Japan have confirmed that the mushroom-based supplement AHCC boosts the immune system in a way that can prevent cancer in elderly people. AHCC is used in over 700 clinics and hospitals in Japan alone to protect the immune system of cancer patients undergoing chemotherapy and radiation. The new research shows that there are substantial benefits to the immune system even in an elderly population. The scientists measured the production of two cytokines, interferon (IFN-?) and tumor necrosis factor (TNF-?) by the white blood cells. Cytokines are chemical messengers used by the immune system to communicate between cells. Interferon (IFN-?), which has both tumor reduction and tumor prevention properties, is the most famous cytokine. Tumor necrosis factor (TNF-?) can boost a person?s immune response, and can also cause necrosis (cell death) of some types of tumor cells. Tumor necrosis factor is being studied in the treatment of some types of cancer. This research shows that the natural production of these immune-boosting and cancer-preventive cytokines by white blood cells increased within four weeks of taking the recommended dose of AHCC. It also shows that the immune-enhancing effect persisted for at least a month after stopping the daily dose. This research helps explain the mechanism by which AHCC prevents immune system collapse in patients undergoing cancer chemotherapy.
 
I have someone moderate allergies, would mushrooms help combat this??
 
The answer is more than likely, yes.

Many of the species are extremely good at modulating the immunesystem and suppressing inflammation as well as histamine release. Or so the research indicates...

But last month I got bit by four times by mosquitos in a day while cleaning my house in the garage. I felt a strong histamine release characterized by the prickly tingly feeling and active sweat glands, higher body temperature and all. It felt pretty bad, but suprisingly after 10-15 minutes my body stopped doing all of that entirely. I forgot about the bug bites and didn't really have any inclination to scratch them from the start. In the first hour they were very large flat red patches with a small bite in the center, the nodule looking center just like usual. They looked more inflammed than a typical mosquito bite though. It kept worrying me for a few hours, but for some reason I never felt all that itchy. I realized this later in the day, I hadn't been scratching the bites at all. In fact, I totally forgot about them..

So I woke up the next morning and checked the bites when I remembered, and to my suprise I could hardly even find them. The only evidence left of a mosquito bite was a small red speck and perhaps a very very light pink ring fading around them. So in less than 12 hours my bites dissapeared and didn't itch one bit, if anything they only tingled a little.

I got a couple more bites a couple weeks ago and in only 4 hours the bites reduced to the same tiny red spots then dissipated the next morning. No itching.

Needless to say I don't know how to explain it other than the mushrooms i'm eating. Mosquito bites are protein immunomodulating reactions, their injection modulates cell targets and causes allergic reactions. Allergies are the result of compromised immune systems. If your allergies are the common outdoor pollen/spore allergies most people experience, then it will help that too probably. I know I breathe easy now, my nose never gets stopped up with mucus and i'm never sneezing. But keep in mind I never really suffered much from outdoor allergies.

So yes, I think these will help your problem.
 
I'm going to give them a whirl. looking on amazon right now
 
Yeah :) he's a quirky guy, absolutely geeks out about mushrooms and fungi in general. but the man is absolutely brilliant and considered and in mycology he's extremely well known and respected.
 
I'm going to give them a whirl. looking on amazon right now

the fungi perfecti blends grown by paul stamets are sold on amazon but i'm not entirely sure if its the best deal, personally i like dealing with iherb.com. they also have great prices and service. ive seen a few other retailers online selling them.

theres also mushroomharvest.com, owned by a botanist specializing in mycology. he's a very knowledgable guy and his blends are standardized and of very high quality.
 
Psilocybe cubensis.....that's the only medicine I need....
 
Psilocybe cubensis.....that's the only medicine I need....

I'm fanatical about these types of mushrooms as well, but halflife2.net isn't really the place for discussion of psychadelics. Everyone knows they're fun/interesting/theraputic anyways. :) Psilocybe cyanescens is also wonderful.

other interesting medicinal properties of mushrooms:

- the chaga mushroom has an ORAC (measure of free radical scavenging) rating higher than any other antioxidant containing edible food, so high that it has four times the antioxidants of acai berries. ORAC value comes out to about 80,000 as opposed to about 20,000 in acai. the antioxidants are also among the most potent free radical scavengers that have been identified.
- the cordyceps mushroom has for a long time been to increase indurance and stamina as well as increasing the efficiency in which your body utilizes oxygen.. but check this interesting story out:

Outside the East, the world was largely unaware of cordyceps.[dubious – discuss] This changed when the fungus caught the world's attention due to three female Chinese athletes, Wang Junxia, Qu Yunxia, and Zhang Linli.[citation needed] These athletes broke 5 world records for 1,500, 3,000 and 10,000 meters in 1993 at the National Games in Beijing, China. The amount of new world records being set at a single track event caused much attention and suspicion. Following the races, the women were expected by some to fail drug tests for anabolic steroids. However, the athletes' tests revealed no illegal substances, and coach Ma Junren told reporters that the runners were taking Cordyceps at his request.

- the lion's mane mushroom has recently in research been found to host a Nerve Growth Factor (NGF) stimulating substance called hericenones. NGF are substances which control the lifespan and regeneration of nerve tissue. hericenones have the unique ability, unlike previously isolated NGF agents, to pass completely unhinged through the blood brain barrier and stimulate the regeneration of the other type of nerve, the neuron.
funnily enough a prelimary study on 65-85 year olds with cognitive disfunction proved quite successful with lion's mane, and they significantly reduced the cognitive disfunction of almost every patient involved. this has shown promise as an agent to not just slow down dementia and alzheimers, but reverse and actually treat them.
 
May I ask why you disapprove?
I've made every attempt to throw credible resources into this thread in attempt to inform people about medicinal mushrooms.
Sorry you didn't take the time to read the information i've provided.
 
I disapprove of this thread because of the potential danger it forms. You act like you are a physician while you clearly aren't. Example:

- the cordyceps mushroom has for a long time ...

Cordyceps isn't the species, but it is a genus with 400 different species. Let me write that in letters for you: four hundred. Some of those four hundred different species supposedly have medicinal qualities, but others kill ants. Get your facts straight.
 
I'm offering here what I know, and I am not perfect. I am not a physician but these mushrooms offer great medicinal potential and I am trying to let people know. For your information many of them have shown anti-fungal properties as well, so yes his fungal allergens would probably benefit from ingestion of them.

Most people shorthand cordyceps sinensis to just cordyceps, but the information I have posted here is true. Fine, when I say cordyceps I really mean cordyceps sinensis. Any product you can buy containing "cordyceps" will be produced using that same species, so whats the difference? How am I not well informed? I've every study, study abstract, research review, and anything else I can get my hands on. Would you prefer I read the multitude of bullshit websites copy/pasting information from the credible sources about them? I try to avoid random .coms and news aggregates posting articles some joe shmoe wrote.

And my story about my mosquito bites is true. Its what I observed on my own body in a period of 24 hours, sorry if my own personal testimony is not enough for you. Mosquito bites are an immunological response, mushrooms are capable of fortifying the immune system in a multitude of ways.

He asked if they would help, I said: Yes, they probably will.
I stand by my statement based off of my personal experiences and quite frankly in the coming months if he tries them you may hear the same thing from him.



But for the record, NO I am not a doctor or a physician. I am a person who has managed turned my entire life around because of Paul Stamets and his team of mycologists. It is a FACT that people HAVE and CAN benefit from these mushrooms, but just how much is not certain yet.

And no I am making no money from any of this.. I've actually lost money giving these things to my friends get them started, because I believe passionately in medicinal mushrooms and their potential.
 
I fully endorse this product and/or event.
 
I'll be purchasing some of this mushroom blend in the future.
 
I am Commander Shephard and these are my favorite mushrooms in the galaxy.
 
http://blog.mycology.cornell.edu/?p=1130

there's the history behind the agarikon mushroom and its cultural use as a remedy for sickness and disease.

http://intraspec.ca/mycomedicine/Antiviral_activity_from_medicinal_mushro.pdf

and that is the patent application filed suggesting the defensive use of mushroom species, in particular the agarikon, in extracts to defend against viruseses. once again, a hard read. but his patent is thorough and references published research often.

that same website hosts many other research PDFs.
http://intraspec.ca/mycomedicine/


I like to think that i'm posting links to scientific literature, cancer charities, cancer centers, and educational institutions that are consistent in regard to the claims being made.

The constituents such as polysaccharide beta-glucans, ganoderic acids, PSK, PSP, alpha-glucosidase inhibitor, lovastatin, eritadenine, vitamin D, conjugated linoleic acid, proteinase inhibitors, triterpenes, D-fraction polysaccharides, acetylated ?-glucan, proflamin,betulin, inotodiol, eranacines, and a plethora of anti-oxidants are all involved.

Information about them can easily be found on pubmed as well as other reputable sources, some of which are posted earlier.

If you had told me before two and a half months ago whether I would believe any of this I probably would have had the same reaction as you. I am a skeptic at heart, first and foremost. But I tried them after discovering fungi.com, Paul Stamets website, and picked up New Chapter Mycomend as well as NOW Foods Reishi/Shiitake capsules then progressed up to my current intake of Fungi Perfecti products. And I now know that he is not a liar, his products really do stimulate the immune system in a way I never thought possible. I have lost weight, I have lost my acne, I now have triple the indurance and stamina in exercise than I did 2 months ago, and I only started exercising after the first month in. I experience a significantly reduced stress response in my body and mind, my joints and muscles rarely ache and it takes tremendous physical exertion to render them into any state of bothersome pain at all. I can focus easier on tasks I am doing, I feel as if I am more patient. I lost my craving for cigarettes that I couldn't give up entirely after months of bumming cigarettes from coworkers. I have watched every bug bite as of recently disappear tremendously quick and without itching. To follow up my previous experience, I received three more bug bites last night and could not find them within hours, nor could my roomate. A coworker noticed I had a patch that resembled poison oak, and was sure I had gotten poison oak, but the patches of red only inflammed for a matter of hours then began receding into my skin. Once agian, whatever it was was gone entirely in a couple days. Poison oak is an allergic reaction and thus an immune system response in the body as well. Quite frankly I just feel much better in general, a sense of well-being that is unlike narcotics and feels entirely like me being healthy.

So thats my personal account, and thats what i'm offering up here for others to possibly benefit from as well. I didn't just join hl2.net years ago to finally try and sell you some crackpot medicine years later. I gain nothing from any of this and continue responding to the thread in the genuine hope that you may benefit as I have. Can you not atleast see my modest intentions before you slander my posts on the basis that they are unrelated and TLDR? I would completely be down for letting any one of you call my cell phone in my spare time and i'll explain in further detail my experience.
 
Keifer made from some Tibetan Milk Mushroom is pretty awesome!
 
Oh cool, so do you have some articles from mainstream peer-reviewed journals to back all this up or just ones from an interest group's website?
If it's the latter I'll no more believe in this than in homeopathy.
 
Oh cool, so do you have some articles from mainstream peer-reviewed journals to back all this up or just ones from an interest group's website?
If it's the latter I'll no more believe in this than in homeopathy.

This. Thefiznut sounds like someone who has been recently converted. Not reliable at all.
 
Interest group?
I posted links to a cancer research center, a really well known one at that. You think Sloan Kettering is some kind of joke?
Stamets you can trust, he's one of the most well respected figures in mycology and considered a master cultivator. He has studied fungi for 35 years after attending
The American Cancer society?
Cancer Research UK?

These are large well-known institutions and you're saying i'm quoting interest groups? I don't even feel like you read any of what I posted. Would you prefer I started linking to PubMed studies? Because thats where most of the research is hosted anyways. Medicinal mushroom research has been ongoing globally for 50 years, its not new and not a scam.

If you're going to mock me and call me liar and a homeopathic quack please refrain from posting in this thread. I know I feel 400% better after two months of eating them, and its a fact that these mushrooms have anti-cancerous qualities, a fact known globally seemingly everywhere but the US.

I really don't know where you're getting that i'm unreliable? There's studies all over pubmed suggesting that mushrooms modulate the immune system in a myriad of ways in eukaryotic animal immune systems.
 
Fact: Fungal mycelia are the harbingers of all life on Earth, and seeded the Earth's atmosphere with oxygen.

Fact: The most powerful antibiotics and antivirals are developed with the help of, or discovered within, naturally-occuring fungi. These are also safer than wholly-artificial pharmaceuticals.

Just saying.
 
Adachi, Y., M. Okazaki, N. Ohno, and T. Yadomae, 1994. "Enhancement of cytokine production by macrophages stimulated with (1—3)-beta-D-glucan, grifolan (GRN), isolated from Grifola frondosa. Biol. Phar. Bull. Dec; 17(12)1554-60.

Adachi, et al. 1988. "Blood pressure lowering activity present in the fruitbody of Grifola frondosa (Maitake). "Chemical and Pharmaceutical Bulletin 3: 1000-1006.

Adachi, K. et al., 1987. "Potentiation of host-mediated antitumor activity in mice by B-glucan obtained from Grifola frondosa (Maitake)" Chemical and Pharmaceutical Bulletin 35:262-270.

Andreacchi, A. 1995. "Characterization of AA 567, a coronary vasodilator and ca-channel antagonist produced by a basidiomycete species YL 8006." Ph.D. Dissertation, University of Rochester, Dept. of Chemical Engineering.

Chen, A. & P. Miles, 1996. "Biomedical research and the application of mushroom nutraceuticals from Ganoderma lucidum" in Mushroom Biology and Mushroom Products, Penn State University, University Park, Pa.

Chen, W.C., D.M. Hau, C.C. Wang, I.H. Lin, and S.S. Lee., 1995 "Effects of Ganoderma lucidum and Krestin on subset T-cell in spleen of gamma-irradiated mice." American Journal of Chinese Medicine. American Journal of Chinese Medicine 23(3-4): 289-98.

Chihara, G. et al., 1969. Inhibition of mouse sarcoma 180 by polysaccharides from Lentinus edodes (Berk.) Sing. Nature 222: 637-688.

Chihara, G., 1987. "Antitumor and metastasis-inhibitory activities of lentinan as an immunomodulator: an overview". Cancer Det. Prev. Suppl. 1: 423-443.

Collins, R.A., and T.B. Ng, 1997. "Polysaccharopeptide from Coriolus versicolor has potential for use against human immunodeficiency virus type 1 infection" Life Sciences 60(25): PL383-7.

and there's more. look any of these up and read. most can be found on PubMed, which i'm sure you are acquainted with.
 
Wang, S.Y., M.L. Hsu, H.C. Hsu, C.H. Tzeng, S.S. Le, M.S. Shiao, & C.K. Ho, 1997. "The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes." International Journal of Cancer. 70(6): 669-705.

Tsujinaka, T., M. Yokota, J. Kambayashi, M.C. Ou, Y. Kido, and T. Mori, 1990. "Modification of septic processes by beta-glucan administration" European Surgical Research 22(6): 340-346.

Tochikura et al., 1987. "A biological response modifier, PSK, inhibits immunodeficiency virus infection in vitro." Biochem. Biophys. Res. Commun. 148: 726-733.

Takeyama, T., I. Suzuki, N. Ohno, S. Oikawa, K. Sato, M. Ohsawa, T. Yadomae, 1987. "Host-mediated antitumor effect of Grifolan NMF-5N, a polysaccharide obtained from Grifola frondosa" Journal of Pharmicobio-dynamics Nov. 10(11): 644-51.

Tao, J. and K.Y. Feng, 1990. "Experimental and clinical studies on inhibitory effect of Ganoderma lucidum on platelet aggregation" Journal of Tongji Medical University 10(4): 240-3.

Sugimachi, K., T. Akachi, and A. Yamakawa, 1995. "Hypocholesterolemic action of eritadenine is mediated by a modification of hepatic phospholipid metabolism in rats." Journal of Nutrition Aug. 125(8): 2133-2144.

Suzuki, I., T. Itani, N. Ohno, S. Oikawa, K. Sato, T. Miyazaki, T. Yadomae, 1984. "Antitumor activity of a polysaccharide fraction extracted from cultured fruitbodies of Grifola frondosa." Journal of Pharmacobiodyn. Jul; 7(7): 492-500.

Suzuki, I.,, K. Hashimoto, S. Oikawa, K. Sato, M. Osawa, T. Yadomae, 1989. "Antitumor and immunomodulating activities of a beta-glucan obtained from liquid-cultured Grifola frondosa." Chemical and Pharmaceutical Bulletin Feb; 37(2): 410-3.

loads more..
 
I'm not disputing anything here, not saying that they're not helpful, I don't know, but they sound like miracle cures capable of fixing anything and miracle cures don't exist. There is no such thing as a free lunch.
 
But there is such thing as the immune system, which regulates most of the body's functions.

But hey, don't take it from me I guess, because I don't know what i'm talking about. :)

http://uhaweb.hartford.edu/bugl/immune.htm

Blood, lymph, skin, mucosal system, histamines, digestive system, etc. It's a layered defense system of biological processes, and there are cells that activate cascades of cellular activity, such as cytokines, macrophages, phagocytes, T-cells, etc. All part of the innate and adaptive immune systems. If you look around it is really not hard at all to find published research on PubMed even about the increased presence and activity of these cells in mushroom extract testing.
 
Lentinan, a beta-glucan nutritional supplement isolated from the shitake mushroom (Lentula edodes), is a biological response modifier with immunostimulatory properties. Concomitantly, the role of beta-glucans as chemoimmunotherapeutic in a number of solid cancers has been widely documented. We investigated the effects of nutritional grade lentinan upon BN rats and in a preclinical syngeneic model of acute myeloid leukemia. BN rats supplemented daily with lentinan exhibited weight gains, increased white blood cells, monocytes, and circulating cytotoxic T-cells; and had a reduction in anti-inflammatory cytokines IL-4, IL-10, and additionally IL-6. Lentinan treatment of BN rats with BNML leukemia resulted in improved cage-side health and reduced cachexia in the terminal stage of this aggressive disease. Combination of lentinan with standards of care in acute myeloid leukemia, idarubicin, and cytarabine increased average survival compared with monotherapy and reduced cachexia. These results indicate that nutritional supplementation of cancer patients with lentinan should be further investigated.

Lentinan: hematopoietic, immunological, and efficacy studies in a syngeneic model of acute myeloid leukemia.
McCormack E, Skavland J, Mujic M, Bruserud Ø, Gjertsen BT.

Haukeland University Hospital, Bergen, Norway.



Bone marrow myelotoxicity is a major limitation of chemotherapy. While granulocyte colony stimulating factor (G-CSF) treatment is effective, alternative approaches to support hematopoietic recovery are sought. We previously found that a beta-glucan extract from maitake mushroom Grifola frondosa (MBG) enhanced colony forming unit-granulocyte monocyte (CFU-GM) activity of mouse bone marrow and human hematopoietic progenitor cells (HPC), stimulated G-CSF production and spared HPC from doxorubicin toxicity in vitro. This investigation assessed the effects of MBG on leukocyte recovery and granulocyte/monocyte function in vivo after dose intensive paclitaxel (Ptx) in a normal mouse. After a cumulative dose of Ptx (90-120 mg/kg) given to B6D2F1mice, daily oral MBG (4 or 6 mg/kg), intravenous G-CSF (80 microg/kg) or Ptx alone were compared for effects on the dynamics of leukocyte recovery in blood, CFU-GM activity in bone marrow and spleen, and granulocyte/monocyte production of reactive oxygen species (ROS). Leukocyte counts declined less in Ptx + MBG mice compared to Ptx-alone (p = 0.024) or Ptx + G-CSF treatment (p = 0.031). Lymphocyte levels were higher after Ptx + MBG but not Ptx + G-CSF treatment compared to Ptx alone (p < 0.01). MBG increased CFU-GM activity in bone marrow and spleen (p < 0.001, p = 0.002) 2 days after Ptx. After two additional days (Ptx post-day 4), MBG restored granulocyte/monocyte ROS response to normal levels compared to Ptx-alone and increased ROS response compared to Ptx-alone or Ptx + G-CSF (p < 0.01, both). The studies indicate that oral MBG promoted maturation of HPC to become functionally active myeloid cells and enhanced peripheral blood leukocyte recovery after chemotoxic bone marrow injury.

Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity.
Lin H, de Stanchina E, Zhou XK, Hong F, Seidman A, Fornier M, Xiao WL, Kennelly EJ, Wesa K, Cassileth BR, Cunningham-Rundles S.

Cellular Immunology Laboratory, Division of Hematology/Oncology, Department of Pediatrics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10065, USA.


Why do you think the cullular immunology laboratory at Cornell University would be testing the maitake mushroom taken orally in their labs? And one of the highest volume university hospital in Norway? Seriously, I am not alone. There are scientists and doctors who are studying these mushrooms who feel they have promise in cancer treatments and other immunological diseases. Stop calling me a homeopathic quack, it is not necessary.
 
Bro you've been here since '04, learn to use the edit button.
 
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